4JQI
Structure of active beta-arrestin1 bound to a G protein-coupled receptor phosphopeptide
Summary for 4JQI
Entry DOI | 10.2210/pdb4jqi/pdb |
Descriptor | Beta-arrestin-1, Fab30 heavy chain, Fab30 light chain, ... (8 entities in total) |
Functional Keywords | arrestin, gpcr, g-protein coupled receptor, signaling, signaling protein |
Biological source | Rattus norvegicus (brown rat,rat,rats) More |
Cellular location | Cytoplasm: P29066 Cell membrane; Multi-pass membrane protein: 4JQI |
Total number of polymer chains | 4 |
Total formula weight | 98112.13 |
Authors | Shukla, A.K.,Manglik, A.,Kruse, A.C.,Xiao, K.,Reis, R.I.,Tseng, W.C.,Staus, D.P.,Hilger, D.,Uysal, S.,Huang, L.H.,Paduch, M.,Shukla, P.T.,Koide, A.,Koide, S.,Weis, W.I.,Kossiakoff, A.A.,Kobilka, B.K.,Lefkowitz, R.J. (deposition date: 2013-03-20, release date: 2013-04-17, Last modification date: 2023-09-20) |
Primary citation | Shukla, A.K.,Manglik, A.,Kruse, A.C.,Xiao, K.,Reis, R.I.,Tseng, W.C.,Staus, D.P.,Hilger, D.,Uysal, S.,Huang, L.Y.,Paduch, M.,Tripathi-Shukla, P.,Koide, A.,Koide, S.,Weis, W.I.,Kossiakoff, A.A.,Kobilka, B.K.,Lefkowitz, R.J. Structure of active beta-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide. Nature, 497:137-141, 2013 Cited by PubMed: 23604254DOI: 10.1038/nature12120 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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