4JL9

Crystal structure of mouse TBK1 bound to BX795

4JL9 の概要

• エントリーDOI: 10.2210/pdb4jl9/pdb
• 分子名称: Serine/threonine-protein kinase TBK1, N-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide (2 entities in total)
• 機能のキーワード: protein kinase, kinase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Mus musculus (mouse)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 76281.84

構造登録者

Li, P.,Shu, C. (登録日: 2013-03-12, 公開日: 2013-06-19, 最終更新日: 2024-02-28)

• 主引用文献: Shu, C.,Sankaran, B.,Chaton, C.T.,Herr, A.B.,Mishra, A.,Peng, J.,Li, P.; Structural Insights into the Functions of TBK1 in Innate Antimicrobial Immunity.; Structure, 21:1137-1148, 2013; PubMed: 23746807; DOI: 10.1016/j.str.2013.04.025

実験手法

X-RAY DIFFRACTION (3.0999 Å)