4JL7
Crystal Structure of the Chemokine Receptor CXCR2 in Complex with the First PDZ Domain of NHERF1
Summary for 4JL7
Entry DOI | 10.2210/pdb4jl7/pdb |
Descriptor | Na(+)/H(+) exchange regulatory cofactor NHE-RF1, CHLORIDE ION (3 entities in total) |
Functional Keywords | cxcr2, nherf1, neutrophil, inflammatory diseases, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm (By similarity): O14745 |
Total number of polymer chains | 1 |
Total formula weight | 9966.68 |
Authors | Lu, G.,Wu, Y.,Jiang, Y.,Brunzelle, J.,Sirinupong, N.,Li, C.,Yang, Z. (deposition date: 2013-03-12, release date: 2013-10-23, Last modification date: 2024-02-28) |
Primary citation | Lu, G.,Wu, Y.,Jiang, Y.,Wang, S.,Hou, Y.,Guan, X.,Brunzelle, J.,Sirinupong, N.,Sheng, S.,Li, C.,Yang, Z. Structural Insights into Neutrophilic Migration Revealed by the Crystal Structure of the Chemokine Receptor CXCR2 in Complex with the First PDZ Domain of NHERF1. Plos One, 8:e76219-e76219, 2013 Cited by PubMed: 24098448DOI: 10.1371/journal.pone.0076219 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.16 Å) |
Structure validation
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