4JCF
S268F Variant of JC Polyomavirus Major Capsid Protein VP1 in Complex with LSTc
Summary for 4JCF
| Entry DOI | 10.2210/pdb4jcf/pdb |
| Related | 3NXD 3NXG 4JCD 4JCE |
| Related PRD ID | PRD_900046 |
| Descriptor | Major capsid protein VP1, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... (5 entities in total) |
| Functional Keywords | beta-sandwich, jelly roll topology, viral protein, major capsid protein, pml-associated vp1 mutation, lstc receptor motif |
| Biological source | JC polyomavirus (JCPyV) |
| Cellular location | Virion: P03089 |
| Total number of polymer chains | 5 |
| Total formula weight | 151876.92 |
| Authors | Stehle, T.,Stroh, L.J. (deposition date: 2013-02-21, release date: 2013-08-14, Last modification date: 2023-09-20) |
| Primary citation | Maginnis, M.S.,Stroh, L.J.,Gee, G.V.,O'Hara, B.A.,Derdowski, A.,Stehle, T.,Atwood, W.J. Progressive multifocal leukoencephalopathy-associated mutations in the JC polyomavirus capsid disrupt lactoseries tetrasaccharide c binding. MBio, 4:e00247-e00213, 2013 Cited by PubMed: 23760462DOI: 10.1128/mBio.00247-13 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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