4JCA

Crystal Structure of the apo form of the evolved variant of the computationally designed serine hydrolase, OSH55.4_H1. Northeast Structural Genomics Consortium (NESG) Target OR273

Summary for 4JCA

Entry DOI	10.2210/pdb4jca/pdb
Related	4ETJ
Descriptor	serine hydrolase, RUBIDIUM ION, CITRIC ACID, ... (4 entities in total)
Functional Keywords	structural genomics, psi-biology, protein structure initiative, northeast structural genomics consortium (nesg), hydrolase
Biological source	artificial gene
Total number of polymer chains	1
Total formula weight	18085.82
Authors	Kuzin, A.P.,Lew, S.,Rajagopalan, S.,Seetharaman, J.,Tong, S.,Everett, J.K.,Acton, T.B.,Baker, D.,Montelione, G.T.,Tong, L.,Hunt, J.F.,Northeast Structural Genomics Consortium (NESG) (deposition date: 2013-02-21, release date: 2013-03-20, Last modification date: 2023-09-20)
Primary citation	Rajagopalan, S.,Wang, C.,Yu, K.,Kuzin, A.P.,Richter, F.,Lew, S.,Miklos, A.E.,Matthews, M.L.,Seetharaman, J.,Su, M.,Hunt, J.F.,Cravatt, B.F.,Baker, D. Design of activated serine-containing catalytic triads with atomic-level accuracy. Nat.Chem.Biol., 10:386-391, 2014 Cited by PubMed: 24705591 DOI: 10.1038/nchembio.1498 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.411 Å)

Structure validation