4J9O
Human DNA polymerase eta-DNA ternary complex: primer extension after a T:G mispair
Summary for 4J9O
Entry DOI | 10.2210/pdb4j9o/pdb |
Related | 3MR2 4DL2 4DL3 4J9K 4J9L 4J9M 4J9N 4J9P 4J9Q 4J9R 4J9S |
Descriptor | DNA polymerase eta, DNA (5'-D(*T*AP*CP*TP*TP*AP*TP*GP*AP*CP*GP*T)-3'), DNA (5'-D(*T*AP*CP*GP*TP*CP*AP*TP*G)-3'), ... (8 entities in total) |
Functional Keywords | immunoglobulin, a to g transition, misincorporation, wobble base pair, dna polymerase, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: Q9Y253 |
Total number of polymer chains | 3 |
Total formula weight | 55693.89 |
Authors | Zhao, Y.,Gregory, M.,Biertumpfel, C.,Hua, Y.,Hanaoka, F.,Yang, W. (deposition date: 2013-02-16, release date: 2013-05-01, Last modification date: 2023-09-20) |
Primary citation | Zhao, Y.,Gregory, M.T.,Biertumpfel, C.,Hua, Y.J.,Hanaoka, F.,Yang, W. Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta. Proc.Natl.Acad.Sci.USA, 110:8146-8151, 2013 Cited by PubMed: 23630267DOI: 10.1073/pnas.1303126110 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.597 Å) |
Structure validation
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