4J8R

Structure of an octapeptide repeat of the prion protein bound to the POM2 Fab antibody fragment

4J8R の概要

• エントリーDOI: 10.2210/pdb4j8r/pdb
• 分子名称: Light chain of POM2 Fab, Heavy chain of POM2 Fab, Major prion protein, ... (4 entities in total)
• 機能のキーワード: immunoglobulin fold, fab, antibody, octapeptide repeat, mouse prion protein, immune system
• 由来する生物種: Mus musculus; 詳細
• 細胞内の位置: Cell membrane ; Lipid-anchor, GPI-anchor : P04925
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 95912.38

構造登録者

Swayampakula, M.,Baral, P.K.,Kav, N.N.V.,Aguzzi, A.,James, M.N.G. (登録日: 2013-02-14, 公開日: 2013-05-22, 最終更新日: 2023-09-20)

• 主引用文献: Swayampakula, M.,Baral, P.K.,Aguzzi, A.,Kav, N.N.,James, M.N.; The crystal structure of an octapeptide repeat of the Prion protein in complex with a Fab fragment of the POM2 antibody.; Protein Sci., 22:893-903, 2013; PubMed: 23629842; DOI: 10.1002/pro.2270

実験手法

X-RAY DIFFRACTION (2.303 Å)