4J6S

14-3-3gamma complexed with the N-terminal sequence of tyrosine hydroxylase (residues 1-43)

Summary for 4J6S

Entry DOI	10.2210/pdb4j6s/pdb
Descriptor	14-3-3 protein gamma, N-terminal motif of tyrosine hydroxylase (2 entities in total)
Functional Keywords	14-3-3 proteins, peptide binding, dopamine synthesis, signal transduction, regulatory proteins, tyrosine hydroxylase, phosphorylation, hydrolase
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm (By similarity): P61981
Total number of polymer chains	8
Total formula weight	136100.02
Authors	Mileni, M.,Martinez, A.,Stevens, R.C. (deposition date: 2013-02-11, release date: 2013-10-02, Last modification date: 2023-09-20)
Primary citation	Skjevik, A.A.,Mileni, M.,Baumann, A.,Halskau, O.,Teigen, K.,Stevens, R.C.,Martinez, A. The N-terminal sequence of tyrosine hydroxylase is a conformationally versatile motif that binds 14-3-3 proteins and membranes. J.Mol.Biol., 426:150-168, 2014 Cited by PubMed: 24055376 DOI: 10.1016/j.jmb.2013.09.012 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.08 Å)

Structure validation