4J1U
Crystal structure of antibody 93F3 unstable variant
Summary for 4J1U
| Entry DOI | 10.2210/pdb4j1u/pdb |
| Descriptor | antibody 93F3 Light chain, antibody 93F3 Heavy chain (3 entities in total) |
| Functional Keywords | antibody maturation, antibody stability, clonal selection, immune system |
| Biological source | Mus musculus (mouse) More |
| Total number of polymer chains | 6 |
| Total formula weight | 148028.69 |
| Authors | Wang, F. (deposition date: 2013-02-02, release date: 2013-03-13, Last modification date: 2013-05-22) |
| Primary citation | Wang, F.,Sen, S.,Zhang, Y.,Ahmad, I.,Zhu, X.,Wilson, I.A.,Smider, V.V.,Magliery, T.J.,Schultz, P.G. Somatic hypermutation maintains antibody thermodynamic stability during affinity maturation. Proc.Natl.Acad.Sci.USA, 110:4261-4266, 2013 Cited by PubMed: 23440204DOI: 10.1073/pnas.1301810110 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.58 Å) |
Structure validation
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