4IZT

The E41Q mutant of the amidase from Nesterenkonia sp. AN1 showing covalent addition of the acetamide moiety of fluoroacetamide at the active site cysteine

4IZT の概要

• エントリーDOI: 10.2210/pdb4izt/pdb
• 関連するPDBエントリー: 3HKX 4IZS 4IZU 4IZV 4IZW
• 分子名称: Amidase, ACETAMIDE, 2-fluoroacetamide, ... (4 entities in total)
• 機能のキーワード: fluoroacetamide, acetamide, hydrolase-substrate complex, hydrolase/substrate
• 由来する生物種: Nesterenkonia sp. 10004
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 30312.95

構造登録者

Kimani, S.W.,Sewell, B.T. (登録日: 2013-01-30, 公開日: 2014-02-12, 最終更新日: 2024-11-20)

• 主引用文献: Kimani, S.W.,Hunter, R.,Vlok, M.,Watermeyer, J.,Sewell, B.T.; Covalent modifications of the active site cysteine occur as a result of mutating the glutamate of the catalytic triad in the amidase from Nesterenkonia sp.; To be Published,

実験手法

X-RAY DIFFRACTION (1.92 Å)