4IXX

Crystal structure of S213G variant DAH7PS without Tyr bound from Neisseria meningitidis

Summary for 4IXX

Entry DOI	10.2210/pdb4ixx/pdb
Related	4HSN 4HSO
Descriptor	3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, MANGANESE (II) ION, SULFATE ION, ... (4 entities in total)
Functional Keywords	dahp, dahps, dah7ps, tim barrel, allosteric regulation, aromatic biosynthesis, shikimate pathway, tim-barrel, transferase
Biological source	Neisseria meningitidis
Total number of polymer chains	4
Total formula weight	155620.63
Authors	Cross, P.J.,Pietersma, A.L.,Allison, T.M.,Wilson-Coutts, S.M.,Cochrane, F.C.,Parker, E.J. (deposition date: 2013-01-28, release date: 2013-12-11, Last modification date: 2023-09-20)
Primary citation	Cross, P.J.,Pietersma, A.L.,Allison, T.M.,Wilson-Coutts, S.M.,Cochrane, F.C.,Parker, E.J. Neisseria meningitidis expresses a single 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase that is inhibited primarily by phenylalanine. Protein Sci., 22:1087-1099, 2013 Cited by PubMed: 23754471 DOI: 10.1002/pro.2293 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation