4IU0
Crystal structure of Leishmania mexicana arginase in complex with inhibitor ABH
Summary for 4IU0
Entry DOI | 10.2210/pdb4iu0/pdb |
Related | 2AEB 4ITY 4IU1 4IU4 4IU5 |
Descriptor | Arginase, MANGANESE (II) ION, 2(S)-AMINO-6-BORONOHEXANOIC ACID, ... (5 entities in total) |
Functional Keywords | arginase fold, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Leishmania mexicana |
Total number of polymer chains | 1 |
Total formula weight | 36428.42 |
Authors | D'Antonio, E.L.,Ullman, B.,Roberts, S.C.,Gaur Dixit, U.,Wilson, M.E.,Hai, Y.,Christianson, D.W. (deposition date: 2013-01-19, release date: 2013-01-30, Last modification date: 2023-09-20) |
Primary citation | D'Antonio, E.L.,Ullman, B.,Roberts, S.C.,Dixit, U.G.,Wilson, M.E.,Hai, Y.,Christianson, D.W. Crystal structure of arginase from Leishmania mexicana and implications for the inhibition of polyamine biosynthesis in parasitic infections. Arch.Biochem.Biophys., 535:163-176, 2013 Cited by PubMed: 23583962DOI: 10.1016/j.abb.2013.03.015 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.77 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)