4ITL

Crystal structure of LpxK from Aquifex aeolicus in complex with AMP-PCP at 2.1 angstrom resolution

4ITL の概要

• エントリーDOI: 10.2210/pdb4itl/pdb
• 関連するPDBエントリー: 4EHW 4EHX 4EHY
• 分子名称: Tetraacyldisaccharide 4'-kinase, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: membrane protein, kinase, lipid a, p-loop, p-loop containing nucleoside triphosphate hydrolase, disaccharide-1-phosphate 4'-kinase, membrane, transferase, lipid metabolism, tetraacyldisaccharide 4'-kinase
• 由来する生物種: Aquifex aeolicus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 37379.22

構造登録者

Emptage, R.P.,Pemble IV, C.W.,York, J.D.,Raetz, C.R.H.,Zhou, P. (登録日: 2013-01-18, 公開日: 2013-04-03, 最終更新日: 2023-09-20)

• 主引用文献: Emptage, R.P.,Pemble, C.W.,York, J.D.,Raetz, C.R.,Zhou, P.; Mechanistic Characterization of the Tetraacyldisaccharide-1-phosphate 4'-Kinase LpxK Involved in Lipid A Biosynthesis.; Biochemistry, 52:2280-2290, 2013; PubMed: 23464738; DOI: 10.1021/bi400097z

実験手法

X-RAY DIFFRACTION (2.09 Å)