4IRB

Crystal Structure of Vaccinia Virus Uracil DNA Glycosylase Mutant del171-172D4

Summary for 4IRB

• Entry DOI: 10.2210/pdb4irb/pdb
• Related: 2OWQ 2OWR
• Descriptor: Uracil-DNA glycosylase, SULFATE ION, GLYCEROL, ... (5 entities in total)
• Functional Keywords: uracil-dna glycosylase fold in the core: 3 layers (a/b/a); parallel beta-sheet of 4 strands in the order 2134, beta- sheets at n- and c-terminus, dimeric assembly, component of processivity factor, binding partners a20 and dna, dna repair hydrolase, hydrolase, viral protein
• Biological source: Vaccinia virus Western Reserve (VACV)
• Total number of polymer chains: 4
• Total formula weight: 108659.50

Authors

Schormann, N.,Zhukovskaya, N.,Sartmatova, D.,Nuth, M.,Ricciardi, R.P.,Chattopadhyay, D. (deposition date: 2013-01-14, release date: 2014-02-26, Last modification date: 2024-11-06)

• Primary citation: Schormann, N.,Zhukovskaya, N.,Sartmatova, D.,Nuth, M.,Ricciardi, R.P.,Chattopadhyay, D.; Mutations at the dimer interface affect both function and structure of the Vaccinia virus uracil DNA glycosylase; To be Published,

Experimental method

X-RAY DIFFRACTION (2.3 Å)