4IRB

Crystal Structure of Vaccinia Virus Uracil DNA Glycosylase Mutant del171-172D4

4IRB の概要

• エントリーDOI: 10.2210/pdb4irb/pdb
• 関連するPDBエントリー: 2OWQ 2OWR
• 分子名称: Uracil-DNA glycosylase, SULFATE ION, GLYCEROL, ... (5 entities in total)
• 機能のキーワード: uracil-dna glycosylase fold in the core: 3 layers (a/b/a); parallel beta-sheet of 4 strands in the order 2134, beta- sheets at n- and c-terminus, dimeric assembly, component of processivity factor, binding partners a20 and dna, dna repair hydrolase, hydrolase, viral protein
• 由来する生物種: Vaccinia virus Western Reserve (VACV)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 108659.50

構造登録者

Schormann, N.,Zhukovskaya, N.,Sartmatova, D.,Nuth, M.,Ricciardi, R.P.,Chattopadhyay, D. (登録日: 2013-01-14, 公開日: 2014-02-26, 最終更新日: 2023-09-20)

• 主引用文献: Schormann, N.,Zhukovskaya, N.,Sartmatova, D.,Nuth, M.,Ricciardi, R.P.,Chattopadhyay, D.; Mutations at the dimer interface affect both function and structure of the Vaccinia virus uracil DNA glycosylase; To be Published,

実験手法

X-RAY DIFFRACTION (2.3 Å)