4IQH
Crystal Structure Analysis of Dysferlin C2A variant 1 (C2Av1)
Summary for 4IQH
Entry DOI | 10.2210/pdb4iqh/pdb |
Related | 2DMH 3L9B 4IHB |
Descriptor | Dysferlin (2 entities in total) |
Functional Keywords | c2 domain, membrane repair, acidic phospholipid binding, peripheral membrane protein, membrane protein |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane, sarcolemma; Single-pass type II membrane protein: O75923 |
Total number of polymer chains | 3 |
Total formula weight | 42985.57 |
Authors | Sutton, R.B.,Fuson, K.L. (deposition date: 2013-01-11, release date: 2013-12-18, Last modification date: 2023-09-20) |
Primary citation | Fuson, K.,Rice, A.,Mahling, R.,Snow, A.,Nayak, K.,Shanbhogue, P.,Meyer, A.G.,Redpath, G.M.,Hinderliter, A.,Cooper, S.T.,Sutton, R.B. Alternate Splicing of Dysferlin C2A Confers Ca(2+)-Dependent and Ca(2+)-Independent Binding for Membrane Repair. Structure, 22:104-115, 2014 Cited by PubMed: 24239457DOI: 10.1016/j.str.2013.10.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.764 Å) |
Structure validation
Download full validation report