4IQH

Crystal Structure Analysis of Dysferlin C2A variant 1 (C2Av1)

Summary for 4IQH

• Entry DOI: 10.2210/pdb4iqh/pdb
• Related: 2DMH 3L9B 4IHB
• Descriptor: Dysferlin (2 entities in total)
• Functional Keywords: c2 domain, membrane repair, acidic phospholipid binding, peripheral membrane protein, membrane protein
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane, sarcolemma; Single-pass type II membrane protein: O75923
• Total number of polymer chains: 3
• Total formula weight: 42985.57

Authors

Sutton, R.B.,Fuson, K.L. (deposition date: 2013-01-11, release date: 2013-12-18, Last modification date: 2023-09-20)

• Primary citation: Fuson, K.,Rice, A.,Mahling, R.,Snow, A.,Nayak, K.,Shanbhogue, P.,Meyer, A.G.,Redpath, G.M.,Hinderliter, A.,Cooper, S.T.,Sutton, R.B.; Alternate Splicing of Dysferlin C2A Confers Ca(2+)-Dependent and Ca(2+)-Independent Binding for Membrane Repair.; Structure, 22:104-115, 2014; PubMed: 24239457; DOI: 10.1016/j.str.2013.10.001

Experimental method

X-RAY DIFFRACTION (1.764 Å)