4IOO
Crystal Structure of the first bromodomain of BRD4 in complex with N-methyltrimethylacetamide
Summary for 4IOO
Entry DOI | 10.2210/pdb4ioo/pdb |
Related | 4IOQ 4IOR |
Descriptor | Bromodomain-containing protein 4, 1,2-ETHANEDIOL, N-methyltrimethylacetamide, ... (5 entities in total) |
Functional Keywords | bromodomain, low mw fragment, dna binding protein |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: O60885 |
Total number of polymer chains | 1 |
Total formula weight | 15603.03 |
Authors | Lolli, G.,Battistutta, R. (deposition date: 2013-01-08, release date: 2013-10-02, Last modification date: 2024-02-28) |
Primary citation | Lolli, G.,Battistutta, R. Different orientations of low-molecular-weight fragments in the binding pocket of a BRD4 bromodomain. Acta Crystallogr.,Sect.D, 69:2161-2164, 2013 Cited by PubMed: 24100334DOI: 10.1107/S090744491301994X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.25 Å) |
Structure validation
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