4INZ
The crystal structure of M145A mutant of an epoxide hydrolase from Bacillus megaterium
Summary for 4INZ
Entry DOI | 10.2210/pdb4inz/pdb |
Related | 4G00 4G02 4IO0 |
Descriptor | Soluble epoxide hydrolase, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ... (4 entities in total) |
Functional Keywords | a/b hydrolase fold, enzymatic resolution, hydrolase |
Biological source | Bacillus megaterium |
Total number of polymer chains | 2 |
Total formula weight | 70727.41 |
Authors | Kong, X.D.,Zhou, J.H.,Xu, J.H. (deposition date: 2013-01-07, release date: 2014-02-12, Last modification date: 2024-03-20) |
Primary citation | Kong, X.D.,Yuan, S.,Li, L.,Chen, S.,Xu, J.H.,Zhou, J.H. Engineering of an epoxide hydrolase for efficient bioresolution of bulky pharmaco substrates. Proc.Natl.Acad.Sci.USA, 111:15717-15722, 2014 Cited by PubMed: 25331869DOI: 10.1073/pnas.1404915111 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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