4IN9

Structure of karilysin MMP-like catalytic domain in complex with inhibitory tetrapeptide SWFP

Summary for 4IN9

Entry DOI	10.2210/pdb4in9/pdb
Related	2XS3 2XS4
Descriptor	Karilysin protease, Peptide SER-TRP-PHE-PRO, ZINC ION, ... (7 entities in total)
Functional Keywords	matrixin, metallopeptidase, metalloprotease, hydrolytic enzyme, hydrolase
Biological source	Tannerella forsythia More
Cellular location	Secreted : D0EM77
Total number of polymer chains	2
Total formula weight	19892.58
Authors	Guevara, T.,Ksiazek, M.,Skottrup, P.D.,Cerda-Costa, N.,Trillo-Muyo, S.,de Diego, I.,Riise, E.,Potempa, J.,Gomis-Ruth, F.X. (deposition date: 2013-01-04, release date: 2013-05-15, Last modification date: 2023-09-20)
Primary citation	Guevara, T.,Ksiazek, M.,Skottrup, P.D.,Cerda-Costa, N.,Trillo-Muyo, S.,de Diego, I.,Riise, E.,Potempa, J.,Gomis-Ruth, F.X. Structure of the catalytic domain of the Tannerella forsythia matrix metallopeptidase karilysin in complex with a tetrapeptidic inhibitor. Acta Crystallogr.,Sect.F, 69:472-476, 2013 Cited by PubMed: 23695557 DOI: 10.1107/S1744309113007392 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.55 Å)

Structure validation