4IMG

Crystal Structure of Pasteurella multocida N-Acetyl-D-Neuraminic acid lyase K164 mutant complexed with N-Glycolylneuraminic acid

Summary for 4IMG

• Entry DOI: 10.2210/pdb4img/pdb
• Related: 4IMC 4IMD 4IME 4IMF
• Descriptor: N-acetylneuraminate lyase, 3,5-dideoxy-5-[(hydroxyacetyl)amino]-D-glycero-D-galacto-non-2-ulosonic acid, 1-ETHOXY-2-(2-METHOXYETHOXY)ETHANE, ... (4 entities in total)
• Functional Keywords: tim barrel, schiff base, lyase
• Biological source: Pasteurella multocida subsp. gallicida
• Cellular location: Cytoplasm (By similarity): Q9CKB0
• Total number of polymer chains: 2
• Total formula weight: 66986.97

Authors

Fisher, A.J.,Huynh, N. (deposition date: 2013-01-02, release date: 2013-11-06, Last modification date: 2024-02-28)

• Primary citation: Huynh, N.,Aye, A.,Li, Y.,Yu, H.,Cao, H.,Tiwari, V.K.,Shin, D.W.,Chen, X.,Fisher, A.J.; Structural Basis for Substrate Specificity and Mechanism of N-Acetyl-d-neuraminic Acid Lyase from Pasteurella multocida.; Biochemistry, 52:8570-8579, 2013; PubMed: 24152047; DOI: 10.1021/bi4011754

Experimental method

X-RAY DIFFRACTION (1.85 Å)