4IKN

Crystal structure of adaptor protein complex 3 (AP-3) mu3A subunit C-terminal domain, in complex with a sorting peptide from TGN38

Summary for 4IKN

Entry DOI	10.2210/pdb4ikn/pdb
Descriptor	AP-3 complex subunit mu-1, Trans-Golgi network integral membrane protein TGN38 (3 entities in total)
Functional Keywords	immunoglobulin-like beta-sandwich, signal recognition, cytosolic tail of transmembrane proteins, adaptor protein, protein transport
Biological source	Rattus norvegicus (brown rat,rat,rats) More
Cellular location	Golgi apparatus: P53676 Golgi apparatus, trans-Golgi network membrane; Single-pass membrane protein (Potential): P19814
Total number of polymer chains	2
Total formula weight	30121.79
Authors	Mardones, G.A.,Kloer, D.P.,Burgos, P.V.,Bonifacino, J.S.,Hurley, J.H. (deposition date: 2012-12-26, release date: 2013-02-20, Last modification date: 2023-09-20)
Primary citation	Mardones, G.A.,Burgos, P.V.,Lin, Y.,Kloer, D.P.,Magadan, J.G.,Hurley, J.H.,Bonifacino, J.S. Structural basis for the recognition of tyrosine-based sorting signals by the mu 3A subunit of the AP-3 adaptor complex. J.Biol.Chem., 288:9563-9571, 2013 Cited by PubMed: 23404500 DOI: 10.1074/jbc.M113.450775 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.851 Å)

Structure validation