4IKA

Crystal structure of EV71 3Dpol-VPg

4IKA の概要

• エントリーDOI: 10.2210/pdb4ika/pdb
• 分子名称: 3Dpol, VPg, NICKEL (II) ION, ... (4 entities in total)
• 機能のキーワード: rdrp, replication, vpg
• 由来する生物種: Human enterovirus 71; 詳細
• 細胞内の位置: Host cytoplasm (By similarity). Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). Virion (By similarity): I3UIB4 Q0ZSY4
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 55023.76

構造登録者

Chen, C.,Wang, Y.X.,Lou, Z.Y. (登録日: 2012-12-25, 公開日: 2013-09-04, 最終更新日: 2023-11-08)

• 主引用文献: Chen, C.,Wang, Y.X.,Shan, C.,Sun, Y.,Xu, P.,Zhou, H.G.,Yang, C.,Shi, P.Y.,Rao, Z.H.,Zhang, B.,Lou, Z.Y.; Crystal structure of enterovirus 71 RNA-dependent RNA polymerase complexed with its protein primer VPg: implication for a trans mechanism of VPg uridylylation; J.Virol., 87:5755-5768, 2013; PubMed: 23487447; DOI: 10.1128/JVI.02733-12

実験手法

X-RAY DIFFRACTION (2.7 Å)