4IH8
Crystal structure of TgCDPK1 with inhibitor bound
Summary for 4IH8
Entry DOI | 10.2210/pdb4ih8/pdb |
Descriptor | Calmodulin-domain protein kinase 1, 4-Amino-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl-cyclopentane (3 entities in total) |
Functional Keywords | structural genomics, structural genomics consortium, sgc, kinase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Toxoplasma gondii |
Total number of polymer chains | 1 |
Total formula weight | 57703.48 |
Authors | El Bakkouri, M.,Tempel, W.,Crandall, I.,Massad, T.,Loppnau, P.,Graslund, S.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Kain, K.,Hui, R.,Structural Genomics Consortium (SGC) (deposition date: 2012-12-18, release date: 2014-04-16, Last modification date: 2024-02-28) |
Primary citation | El Bakkouri, M.,Tempel, W.,Crandall, I.,Massad, T.,Loppnau, P.,Graslund, S.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Kain, K.,Hui, R.,Structural Genomics Consortium (SGC) Crystal structure of TgCDPK1 with inhibitor bound To be Published, |
Experimental method | X-RAY DIFFRACTION (2.877 Å) |
Structure validation
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