4IE9
Bovine PKA C-alpha in complex with 3-pyridylmethyl-5-methyl-1H-pyrazole-3-carboxylate
Summary for 4IE9
| Entry DOI | 10.2210/pdb4ie9/pdb |
| Descriptor | cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, pyridin-3-ylmethyl 5-methyl-1H-pyrazole-3-carboxylate, ... (5 entities in total) |
| Functional Keywords | protein kinase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
| Biological source | Bos taurus (bovine) More |
| Cellular location | Cytoplasm : P00517 |
| Total number of polymer chains | 2 |
| Total formula weight | 43373.34 |
| Authors | Dreyer, M.K.,Schiffer, A.,Lodge, J. (deposition date: 2012-12-13, release date: 2013-05-01, Last modification date: 2017-11-15) |
| Primary citation | Skjaerven, L.,Codutti, L.,Angelini, A.,Grimaldi, M.,Latek, D.,Monecke, P.,Dreyer, M.K.,Carlomagno, T. Accounting for Conformational Variability in Protein-Ligand Docking with NMR-Guided Rescoring J.Am.Chem.Soc., 135:5819-5827, 2013 Cited by PubMed: 23565800DOI: 10.1021/ja4007468 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.92 Å) |
Structure validation
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