4IB5

Structure of human protein kinase CK2 catalytic subunit in complex with a CK2beta-competitive cyclic peptide

Summary for 4IB5

• Entry DOI: 10.2210/pdb4ib5/pdb
• Related: 1PJK 1jwh 2PVR
• Descriptor: Casein kinase II subunit alpha, CK2beta-derived cyclic peptide, GLYCEROL, ... (5 entities in total)
• Functional Keywords: protein kinase fold, protein phosphorylation, binding of ck2beta, phosphorylation, nucleus, transferase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 7
• Total formula weight: 126790.20

Authors

Raaf, J.,Guerra, B.,Neundorf, I.,Bopp, B.,Issinger, O.-G.,Jose, J.,Pietsch, M.,Niefind, K. (deposition date: 2012-12-08, release date: 2013-03-20, Last modification date: 2013-06-05)

• Primary citation: Raaf, J.,Guerra, B.,Neundorf, I.,Bopp, B.,Issinger, O.G.,Jose, J.,Pietsch, M.,Niefind, K.; First structure of protein kinase CK2 catalytic subunit with an effective CK2 beta-competitive ligand; Acs Chem.Biol., 8:901-907, 2013; PubMed: 23474121; DOI: 10.1021/cb3007133

Experimental method

X-RAY DIFFRACTION (2.2 Å)