4IAX

Engineered human lipocalin 2 (CL31) in complex with Y-DTPA

4IAX の概要

• エントリーDOI: 10.2210/pdb4iax/pdb
• 関連するPDBエントリー: 3DSZ 3DTQ 4IAW
• 分子名称: Neutrophil gelatinase-associated lipocalin, N-{(1S,2S)-2-[bis(carboxymethyl)amino]cyclohexyl}-N-{(2R)-2-[bis(carboxymethyl)amino]-3-[4-({[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]carbamothioyl}amino)phenyl]propyl}glycine, YTTRIUM (III) ION, ... (4 entities in total)
• 機能のキーワード: beta-barrel, engineered lipocalin, binding protein, y-chx-a''-dtpa, strep-tag, transport protein
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Secreted: P80188
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 22370.17

構造登録者

Eichinger, A.,Skerra, A. (登録日: 2012-12-07, 公開日: 2013-06-19, 最終更新日: 2023-11-08)

• 主引用文献: Eggenstein, E.,Eichinger, A.,Kim, H.J.,Skerra, A.; Structure-guided engineering of Anticalins with improved binding behavior and biochemical characteristics for application in radio-immuno imaging and/or therapy; J.Struct.Biol., 185:203-214, 2014; PubMed: 23542582; DOI: 10.1016/j.jsb.2013.03.009

実験手法

X-RAY DIFFRACTION (1.9 Å)