4I9X

Crystal structure of human cytomegalovirus glycoprotein UL141 targeting the death receptor TRAIL-R2

4I9X の概要

• エントリーDOI: 10.2210/pdb4i9x/pdb
• 分子名称: Protein UL141, Tumor necrosis factor receptor superfamily member 10B, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: ig-like domain, apoptosis
• 由来する生物種: Human herpesvirus 5 (HHV-5); 詳細
• 細胞内の位置: Host endoplasmic reticulum membrane; Single- pass membrane protein: Q6RJQ3; Membrane; Single-pass type I membrane protein: O14763
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 80127.38

構造登録者

Nemcovicova, I.,Zajonc, D.M. (登録日: 2012-12-05, 公開日: 2013-04-03, 最終更新日: 2020-07-29)

• 主引用文献: Nemcovicova, I.,Benedict, C.A.,Zajonc, D.M.; Structure of Human Cytomegalovirus UL141 Binding to TRAIL-R2 Reveals Novel, Non-canonical Death Receptor Interactions.; Plos Pathog., 9:e1003224-e1003224, 2013; PubMed: 23555243; DOI: 10.1371/journal.ppat.1003224

実験手法

X-RAY DIFFRACTION (2.1 Å)