Crystal Structure of the R111K:R132L:Y134F:T54V:R59W:A32W Mutant of the Cellular Retinoic Acid Binding Protein Type II in Complex with All-Trans Retinal at 2.6 Angstrom Resolution

Summary for 4I9R

Related2G7B 2G78 2FR3 3F8A 4EXZ 4EEJ 4EFG 3FEP 4I9S
DescriptorCellular retinoic acid-binding protein 2, RETINAL (3 entities in total)
Functional Keywordsprotein engineering, wavelength regulation, ph sensing, pka, retinylidene psb, iminium, transport protein
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm P29373
Total number of polymer chains1
Total molecular weight15920.37
Nosrati, M.,Geiger, J.H. (deposition date: 2012-12-05, release date: 2013-10-09, Last modification date: 2018-01-31)
Primary citation
Berbasova, T.,Nosrati, M.,Vasileiou, C.,Wang, W.,Lee, K.S.,Yapici, I.,Geiger, J.H.,Borhan, B.
Rational Design of a Colorimetric pH Sensor from a Soluble Retinoic Acid Chaperone.
J.Am.Chem.Soc., 135:16111-16119, 2013
PubMed: 24059243 (PDB entries with the same primary citation)
DOI: 10.1021/ja404900k
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.277111.5%7.6%3.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution