4I9J
Structure of the N254Y/H258Y mutant of the phosphatidylinositol-specific phospholipase C from S. aureus bound to diC4PC
Summary for 4I9J
| Entry DOI | 10.2210/pdb4i9j/pdb |
| Related | 4I8Y 4I90 4I9M 4I9T |
| Descriptor | 1-phosphatidylinositol phosphodiesterase, ACETATE ION, (4S,7R)-7-(heptanoyloxy)-4-hydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphahexadecan-1-aminium 4-oxide, ... (4 entities in total) |
| Functional Keywords | tim barrel, phospholipase, dic4pc binding, lyase, hydrolase |
| Biological source | Staphylococcus aureus subsp. aureus |
| Cellular location | Secreted: P45723 |
| Total number of polymer chains | 1 |
| Total formula weight | 36822.99 |
| Authors | Goldstein, R.I.,Cheng, J.,Stec, B.,Gershenson, A.,Roberts, M.F. (deposition date: 2012-12-05, release date: 2013-04-10, Last modification date: 2023-09-20) |
| Primary citation | Cheng, J.,Goldstein, R.,Gershenson, A.,Stec, B.,Roberts, M.F. The cation-pi box is a specific phosphatidylcholine membrane targeting motif. J.Biol.Chem., 288:14863-14873, 2013 Cited by PubMed: 23576432DOI: 10.1074/jbc.M113.466532 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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