4I6N

Crystal structure of Trichinella spiralis UCH37 catalytic domain bound to Ubiquitin vinyl methyl ester

4I6N の概要

• エントリーDOI: 10.2210/pdb4i6n/pdb
• 関連するPDBエントリー: 3IHR
• 分子名称: Ubiquitin carboxyl-hydrolase, Ubiquitin, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ... (6 entities in total)
• 機能のキーワード: helix-beta-helix sandwich, protein-protein complex, deubiquitination, ubiquitin c-terminal hydrolase, cytosol, hydrolase-signaling protein complex, hydrolase/signaling protein
• 由来する生物種: Trichinella spiralis (Trichina worm); 詳細
• 細胞内の位置: Ubiquitin: Cytoplasm (By similarity): P0CG48
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 70074.88

構造登録者

Morrow, M.E.,Ronau, J.A.,White, R.R.,Artavanis-Tsakonas, K.,Das, C. (登録日: 2012-11-29, 公開日: 2013-05-29, 最終更新日: 2023-11-15)

• 主引用文献: Morrow, M.E.,Kim, M.I.,Ronau, J.A.,Sheedlo, M.J.,White, R.R.,Chaney, J.,Paul, L.N.,Lill, M.A.,Artavanis-Tsakonas, K.,Das, C.; Stabilization of an Unusual Salt Bridge in Ubiquitin by the Extra C-Terminal Domain of the Proteasome-Associated Deubiquitinase UCH37 as a Mechanism of Its Exo Specificity.; Biochemistry, 52:3564-3578, 2013; PubMed: 23617878; DOI: 10.1021/bi4003106

実験手法

X-RAY DIFFRACTION (1.701 Å)