4I56
HMG-CoA reductase from pseudomonas mevalonii complexed with dithio-HMG-coa
Summary for 4I56
Entry DOI | 10.2210/pdb4i56/pdb |
Related | 1QAX 1QAY 1R31 1R7I 4I4B 4I64 4I6A 4I6W 4I6Y |
Descriptor | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, (3S,5S,9R,21S)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9,21-tetrahydroxy-8,8,21-trimethyl-10,14-dioxo-19-thioxo-2,4,6-trioxa-18-thia-11,15-diaza-3,5-diphosphatricosan-23-oic acid 3,5-dioxide, SULFATE ION, ... (5 entities in total) |
Functional Keywords | oxidoreductase |
Biological source | Pseudomonas mevalonii |
Total number of polymer chains | 2 |
Total formula weight | 92678.62 |
Authors | Steussy, C.N.,Stauffacher, C.V.,Schmidt, T.,Crichelow, C.J.,Rodwell, V.W.,Wrensford, L.V.,Min, J.,Burgner II, J.W. (deposition date: 2012-11-28, release date: 2013-07-17, Last modification date: 2019-07-17) |
Primary citation | Steussy, C.N.,Critchelow, C.J.,Schmidt, T.,Min, J.K.,Wrensford, L.V.,Burgner, J.W.,Rodwell, V.W.,Stauffacher, C.V. A Novel Role for Coenzyme A during Hydride Transfer in 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase. Biochemistry, 52:5195-5205, 2013 Cited by PubMed: 23802607DOI: 10.1021/bi400335g PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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