4I4K

Streptomyces globisporus C-1027 9-membered enediyne conserved protein SgcE6

4I4K の概要

• エントリーDOI: 10.2210/pdb4i4k/pdb
• 関連するPDBエントリー: 4OVM
• 分子名称: uncharacterized protein SgcJ, CITRIC ACID, TETRAETHYLENE GLYCOL, ... (7 entities in total)
• 機能のキーワード: structural genomics, psi-biology, midwest center for structural genomics, mcsg, enzyme discovery for natural product biosynthesis, natpro, alpha-beta sandwich, unknown function
• 由来する生物種: Streptomyces globisporus
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 31040.28

構造登録者

Kim, Y.,Bigelow, L.,Clancy, S.,Babnigg, J.,Bingman, C.A.,Yennamalli, R.,Lohman, J.R.,Ma, M.,Shen, B.,Phillips Jr., G.N.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG),Enzyme Discovery for Natural Product Biosynthesis (NatPro) (登録日: 2012-11-27, 公開日: 2012-12-12, 最終更新日: 2016-12-07)

• 主引用文献: Huang, T.,Chang, C.Y.,Lohman, J.R.,Rudolf, J.D.,Kim, Y.,Chang, C.,Yang, D.,Ma, M.,Yan, X.,Crnovcic, I.,Bigelow, L.,Clancy, S.,Bingman, C.A.,Yennamalli, R.M.,Babnigg, G.,Joachimiak, A.,Phillips, G.N.,Shen, B.; Crystal structure of SgcJ, an NTF2-like superfamily protein involved in biosynthesis of the nine-membered enediyne antitumor antibiotic C-1027.; J Antibiot (Tokyo), 69:731-740, 2016; PubMed: 27406907; DOI: 10.1038/ja.2016.88

実験手法

X-RAY DIFFRACTION (1.7 Å)