4I48

Structure of HLA-A68 complexed with an HIV Env derived peptide

4I48 の概要

• エントリーDOI: 10.2210/pdb4i48/pdb
• 関連するPDBエントリー: 4HWZ 4HX1
• 分子名称: HLA class I histocompatibility antigen, A-68 alpha chain, Beta-2-microglobulin, 9-mer peptide from Envelope glycoprotein gp160, ... (4 entities in total)
• 機能のキーワード: monomer, peptide presentation, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P01891; Secreted: P61769; Transmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein: Q70626
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 44451.29

構造登録者

Niu, L.,Cheng, H.,Zhang, S.,Tan, S.,Zhang, Y.,Qi, J.,Liu, J.,Gao, G.F. (登録日: 2012-11-27, 公開日: 2013-10-02)

• 主引用文献: Niu, L.,Cheng, H.,Zhang, S.,Tan, S.,Zhang, Y.,Qi, J.,Liu, J.,Gao, G.F.; Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes; Mol.Immunol., 55:381-392, 2013; PubMed: 23566939; DOI: 10.1016/j.molimm.2013.03.015

実験手法

X-RAY DIFFRACTION (2.799 Å)