4HZX
Crystal structure of influenza A neuraminidase N3 complexed with oseltamivir
Summary for 4HZX
Entry DOI | 10.2210/pdb4hzx/pdb |
Related | 3TI6 4HZV 4HZW 4HZY 4HZZ 4I00 |
Descriptor | Neuraminidase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | neuraminidase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Influenza A virus |
Total number of polymer chains | 1 |
Total formula weight | 44630.08 |
Authors | Li, Q.,Qi, J.,Vavricka, C.J.,Gao, G.F. (deposition date: 2012-11-15, release date: 2013-11-06, Last modification date: 2023-11-08) |
Primary citation | Li, Q.,Qi, J.,Wu, Y.,Kiyota, H.,Tanaka, K.,Suhara, Y.,Ohrui, H.,Suzuki, Y.,Vavricka, C.J.,Gao, G.F. Functional and structural analysis of influenza virus neuraminidase N3 offers further insight into the mechanisms of oseltamivir resistance. J.Virol., 87:10016-10024, 2013 Cited by PubMed: 23824808DOI: 10.1128/JVI.01129-13 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)