4HXJ

Crystal structure of SH3:RGT complex

Summary for 4HXJ

• Entry DOI: 10.2210/pdb4hxj/pdb
• Related: 1FMK
• Descriptor: Proto-oncogene tyrosine-protein kinase Src, C-terminal 3-mer peptide from Integrin beta-3 (3 entities in total)
• Functional Keywords: integrin beta-3, c-src kinase, sh3 domain, rgt, thrombosis, cell signaling, blood clotting, signaling protein
• Biological source: Homo sapiens (human); More
• Cellular location: Cell membrane: P12931; Cell membrane; Single-pass type I membrane protein: P05106
• Total number of polymer chains: 3
• Total formula weight: 13779.83

Authors

Xiao, R.,Meng, G. (deposition date: 2012-11-11, release date: 2012-11-28, Last modification date: 2023-11-08)

• Primary citation: Xiao, R.,Xi, X.D.,Chen, Z.,Chen, S.J.,Meng, G.; Structural framework of c-Src activation by integrin beta 3; Blood, 121:700-706, 2013; PubMed: 23169783; DOI: 10.1182/blood-2012-07-440644

Experimental method

X-RAY DIFFRACTION (2 Å)