4HUR
Crystal structure of streptogramin group A antibiotic acetyltransferase VatA from Staphylococcus aureus in complex with acetyl coenzyme A
4HUR の概要
エントリーDOI | 10.2210/pdb4hur/pdb |
関連するPDBエントリー | 4E8L 4HUS |
分子名称 | Virginiamycin A acetyltransferase, ACETYL COENZYME *A, SULFATE ION, ... (7 entities in total) |
機能のキーワード | structural genomics, antibiotic resistance, center for structural genomics of infectious diseases (csgid), niaid, national institute of allergy and infectious diseases, xenobiotic acyltransferase (xat) family, hexapeptide repeat acyltransferase, streptogramin group a antibiotic acetyltransferase, streptogramin group a antibiotics, streptogramin a, virginiamycin m1, dalfopristin, acetyl coenzyme a, coenzyme a, intracellular, transferase |
由来する生物種 | Staphylococcus aureus |
タンパク質・核酸の鎖数 | 3 |
化学式量合計 | 79573.84 |
構造登録者 | Stogios, P.J.,Minasov, G.,Evdokimova, E.,Wawrzak, Z.,Yim, V.,Krishnamoorthy, M.,Di Leo, R.,Courvalin, P.,Savchenko, A.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2012-11-03, 公開日: 2012-11-14, 最終更新日: 2023-09-20) |
主引用文献 | Stogios, P.J.,Kuhn, M.L.,Evdokimova, E.,Courvalin, P.,Anderson, W.F.,Savchenko, A. Potential for Reduction of Streptogramin A Resistance Revealed by Structural Analysis of Acetyltransferase VatA. Antimicrob.Agents Chemother., 58:7083-7092, 2014 Cited by PubMed: 25223995DOI: 10.1128/AAC.03743-14 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.15 Å) |
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