4HSO

Crystal structure of S213G variant DAH7PS from Neisseria meningitidis

Summary for 4HSO

• Entry DOI: 10.2210/pdb4hso/pdb
• Related: 4HSN
• Descriptor: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, TYROSINE, PHOSPHOENOLPYRUVATE, ... (5 entities in total)
• Functional Keywords: dahp, dahps, dah7ps, tim barrel, transferase, allosteric regulation, aromatic biosynthesis, shikimate pathway
• Biological source: Neisseria meningitidis
• Total number of polymer chains: 4
• Total formula weight: 156345.11

Authors

Cross, P.J.,Pietersma, A.L.,Allison, T.M.,Wilson-Coutts, S.M.,Cochrane, F.C.,Parker, E.J. (deposition date: 2012-10-30, release date: 2013-09-11, Last modification date: 2023-09-20)

• Primary citation: Cross, P.J.,Pietersma, A.L.,Allison, T.M.,Wilson-Coutts, S.M.,Cochrane, F.C.,Parker, E.J.; Neisseria meningitidis expresses a single 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase that is inhibited primarily by phenylalanine.; Protein Sci., 22:1087-1099, 2013; PubMed: 23754471; DOI: 10.1002/pro.2293

Experimental method

X-RAY DIFFRACTION (2.1 Å)