4HSO

Crystal structure of S213G variant DAH7PS from Neisseria meningitidis

4HSO の概要

• エントリーDOI: 10.2210/pdb4hso/pdb
• 関連するPDBエントリー: 4HSN
• 分子名称: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, TYROSINE, PHOSPHOENOLPYRUVATE, ... (5 entities in total)
• 機能のキーワード: dahp, dahps, dah7ps, tim barrel, transferase, allosteric regulation, aromatic biosynthesis, shikimate pathway
• 由来する生物種: Neisseria meningitidis
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 156345.11

構造登録者

Cross, P.J.,Pietersma, A.L.,Allison, T.M.,Wilson-Coutts, S.M.,Cochrane, F.C.,Parker, E.J. (登録日: 2012-10-30, 公開日: 2013-09-11, 最終更新日: 2023-09-20)

• 主引用文献: Cross, P.J.,Pietersma, A.L.,Allison, T.M.,Wilson-Coutts, S.M.,Cochrane, F.C.,Parker, E.J.; Neisseria meningitidis expresses a single 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase that is inhibited primarily by phenylalanine.; Protein Sci., 22:1087-1099, 2013; PubMed: 23754471; DOI: 10.1002/pro.2293

実験手法

X-RAY DIFFRACTION (2.1 Å)