4HSI

Glycoprotein B from Herpes simplex virus type 1, A504P/R505G/Q507G/N511G mutant, low-pH

4HSI の概要

• エントリーDOI: 10.2210/pdb4hsi/pdb
• 関連するPDBエントリー: 2gum 3nw8 3nwa 3nwd 3nwf
• 分子名称: Envelope glycoprotein B, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: viral fusion protein, viral envelope, viral protein
• 由来する生物種: Human herpesvirus 1 (HHV-1)
• 細胞内の位置: Virion membrane; Single-pass type I membrane protein (By similarity): P06437
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 317350.48

構造登録者

Heldwein, E.E. (登録日: 2012-10-30, 公開日: 2013-03-27, 最終更新日: 2023-09-20)

• 主引用文献: Vitu, E.,Sharma, S.,Stampfer, S.D.,Heldwein, E.E.; Extensive Mutagenesis of the HSV-1 gB Ectodomain Reveals Remarkable Stability of Its Postfusion Form.; J.Mol.Biol., 425:2056-2071, 2013; PubMed: 23500487; DOI: 10.1016/j.jmb.2013.03.001

実験手法

X-RAY DIFFRACTION (3.101 Å)