4HR1

Structure of PAV1-137, a protein from the virus PAV1 that infects Pyrococcus abyssi.

4HR1 の概要

• エントリーDOI: 10.2210/pdb4hr1/pdb
• 分子名称: Putative uncharacterized protein (3 entities in total)
• 機能のキーワード: helical bundle, unknown function
• 由来する生物種: Pyrococcus abyssi virus 1; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 28977.79

構造登録者

Leulliot, N.,Quevillon-Cheruel, S.,Graille, M.,Geslin, C.,Flament, D.,Romancer, M.L.,Tilbeurgh, H.V. (登録日: 2012-10-26, 公開日: 2013-06-19, 最終更新日: 2024-11-13)

主引用文献

Leulliot, N.,Quevillon-Cheruel, S.,Graille, M.,Geslin, C.,Flament, D.,Romancer, M.L.,Tilbeurgh, H.V.
Crystal structure of PAV1-137: a protein from the virus PAV1 that infects Pyrococcus abyssi
Archaea, 2013:568053-568053, 2013

PubMed Abstract: Pyrococcus abyssi virus 1 (PAV1) was the first virus particle infecting a hyperthermophilic Euryarchaeota (Pyrococcus abyssi strain GE23) that has been isolated and characterized. It is lemon shaped and is decorated with a short fibered tail. PAV1 morphologically resembles the fusiform members of the family Fuselloviridae or the genus Salterprovirus. The 18 kb dsDNA genome of PAV1 contains 25 predicted genes, most of them of unknown function. To help assigning functions to these proteins, we have initiated structural studies of the PAV1 proteome. We determined the crystal structure of a putative protein of 137 residues (PAV1-137) at a resolution of 2.2 Å. The protein forms dimers both in solution and in the crystal. The fold of PAV1-137 is a four- α -helical bundle analogous to those found in some eukaryotic adhesion proteins such as focal adhesion kinase, suggesting that PAV1-137 is involved in protein-protein interactions.

PubMed: 23533329
DOI: 10.1155/2013/568053

実験手法

X-RAY DIFFRACTION (2.5 Å)