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4HPU

Crystal structure of the catalytic subunit of cAMP-dependent protein kinase displaying partial phosphoryl transfer of AMP-PNP onto a substrate peptide

Summary for 4HPU
Entry DOI10.2210/pdb4hpu/pdb
Related4HPT
DescriptorcAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, MYRISTIC ACID, ... (6 entities in total)
Functional Keywordsprotein kinase fold, phosphotransferase, regulatory subunits, pki, magnesium, phosphorylation, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological sourceMus musculus (mouse)
More
Cellular locationCytoplasm . Isoform 2: Cell projection, cilium, flagellum : P05132
Total number of polymer chains2
Total formula weight44306.03
Authors
Bastidas, A.C.,Steichen, J.M.,Wu, J.,Taylor, S.S. (deposition date: 2012-10-24, release date: 2013-03-20, Last modification date: 2017-11-15)
Primary citationBastidas, A.C.,Deal, M.S.,Steichen, J.M.,Guo, Y.,Wu, J.,Taylor, S.S.
Phosphoryl transfer by protein kinase a is captured in a crystal lattice.
J.Am.Chem.Soc., 135:4788-4798, 2013
Cited by
PubMed: 23458248
DOI: 10.1021/ja312237q
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.55 Å)
Structure validation

217705

数据于2024-03-27公开中

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