4HP1

Crystal structure of Tet3 in complex with a non-CpG dsDNA

4HP1 の概要

• エントリーDOI: 10.2210/pdb4hp1/pdb
• 関連するPDBエントリー: 4HP3
• 分子名称: DNA (5'-D(*GP*CP*CP*AP*CP*(5CM)P*GP*GP*TP*GP*GP*C)-3'), LOC100036628 protein, ZINC ION, ... (4 entities in total)
• 機能のキーワード: cxxc, dna methylation, structural genomics, structural genomics consortium, sgc, dna binding protein-dna complex, dna binding protein/dna
• 由来する生物種: Xenopus (Silurana) tropicalis (Western clawed frog)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 15917.68

構造登録者

Chao, X.,Tempel, W.,Bian, C.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Structural Genomics Consortium (SGC) (登録日: 2012-10-23, 公開日: 2012-12-05, 最終更新日: 2024-04-03)

• 主引用文献: Xu, Y.,Xu, C.,Kato, A.,Tempel, W.,Abreu, J.G.,Bian, C.,Hu, Y.,Hu, D.,Zhao, B.,Cerovina, T.,Diao, J.,Wu, F.,He, H.H.,Cui, Q.,Clark, E.,Ma, C.,Barbara, A.,Veenstra, G.J.,Xu, G.,Kaiser, U.B.,Liu, X.S.,Sugrue, S.P.,He, X.,Min, J.,Kato, Y.,Shi, Y.G.; Tet3 CXXC Domain and Dioxygenase Activity Cooperatively Regulate Key Genes for Xenopus Eye and Neural Development.; Cell(Cambridge,Mass.), 151:1200-1213, 2012; PubMed: 23217707; DOI: 10.1016/j.cell.2012.11.014

実験手法

X-RAY DIFFRACTION (2.25 Å)