4HNO

High resolution crystal structure of DNA Apurinic/apyrimidinic (AP) endonuclease IV Nfo from Thermatoga maritima

4HNO の概要

• エントリーDOI: 10.2210/pdb4hno/pdb
• 分子名称: Probable endonuclease 4, ZINC ION, MANGANESE (II) ION, ... (8 entities in total)
• 機能のキーワード: endonuclease 4, endodeoxyribonuclease iv, endo iv, nfo, metalloprotein, dna damage, dna repair, base excision repair, hydrolase
• 由来する生物種: Thermotoga maritima
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 33223.72

構造登録者

Shin, D.S.,Hosfield, D.J.,Arvai, A.S.,Tsutakawa, S.E.,Tainer, J.A. (登録日: 2012-10-20, 公開日: 2013-01-23, 最終更新日: 2023-09-20)

• 主引用文献: Tsutakawa, S.E.,Shin, D.S.,Mol, C.D.,Izumi, T.,Arvai, A.S.,Mantha, A.K.,Szczesny, B.,Ivanov, I.N.,Hosfield, D.J.,Maiti, B.,Pique, M.E.,Frankel, K.A.,Hitomi, K.,Cunningham, R.P.,Mitra, S.,Tainer, J.A.; Conserved Structural Chemistry for Incision Activity in Structurally Non-homologous Apurinic/Apyrimidinic Endonuclease APE1 and Endonuclease IV DNA Repair Enzymes.; J.Biol.Chem., 288:8445-8455, 2013; PubMed: 23355472; DOI: 10.1074/jbc.M112.422774

実験手法

X-RAY DIFFRACTION (0.9194 Å)