4HL1

Crystal Structure of New Delhi Metallo-beta-Lactamase-1, Complexed with Cd and Ampicillin

4HL1 の概要

• エントリーDOI: 10.2210/pdb4hl1/pdb
• 関連するPDBエントリー: 3RKJ 3RKK 3SBL 3SFP 3SRX 4GYQ 4GYU 4H0D 4HKY 4HL2
• 分子名称: Beta-lactamase NDM-1, (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, CADMIUM ION, ... (5 entities in total)
• 機能のキーワード: structural genomics, psi-biology, midwest center for structural genomics, mcsg, structures of mtb proteins conferring susceptibility to known mtb inhibitors, mtbi, alpha-beta-beta-alpha sandwich, hydrolase, hydrolase-antibiotic complex, hydrolase/antibiotic
• 由来する生物種: Klebsiella pneumoniae
• 細胞内の位置: Periplasm (Potential): C7C422
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 52916.04

構造登録者

Kim, Y.,Tesar, C.,Jedrzejczak, R.,Babnigg, J.,Mire, J.,Sacchettini, J.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG),Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI) (登録日: 2012-10-15, 公開日: 2012-12-12, 最終更新日: 2023-09-20)

• 主引用文献: Kim, Y.,Tesar, C.,Jedrzejczak, R.,Babnigg, J.,Mire, J.,Sacchettini, J.,Joachimiak, A.; Crystal Structure of New Delhi Metallo-beta-Lactamase-1, Complexed with Cd and Ampicillin; To be Published,

実験手法

X-RAY DIFFRACTION (1.5 Å)