4HKJ

Structure of Cowpox CPXV203 in complex with MHCI (H-2Kb)

4HKJ の概要

• エントリーDOI: 10.2210/pdb4hkj/pdb
• 分子名称: H-2 class I histocompatibility antigen, K-B alpha chain, Beta-2-microglobulin, Ovalbumin, ... (5 entities in total)
• 機能のキーワード: viral immune evasion proteins, antigen presentation, structural genomics, niaid, national institute of allergy and infectious diseases, center for structural genomics of infectious diseases, csgid, inhibitor, intracellular, immune system-viral protein complex, immune system/viral protein
• 由来する生物種: Mus musculus (mouse); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P01901; Secreted . Note=(Microbial infection) In the presence of M: P61769; Secreted : P01012
• タンパク質・核酸の鎖数: 16
• 化学式量合計: 275987.25

構造登録者

McCoy IV, W.H.,Fremont, D.H.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2012-10-15, 公開日: 2012-11-14, 最終更新日: 2023-12-06)

• 主引用文献: McCoy, W.H.,Wang, X.,Yokoyama, W.M.,Hansen, T.H.,Fremont, D.H.; Structural Mechanism of ER Retrieval of MHC Class I by Cowpox.; Plos Biol., 10:e1001432-e1001432, 2012; PubMed: 23209377; DOI: 10.1371/journal.pbio.1001432

実験手法

X-RAY DIFFRACTION (3 Å)