4HK6

Crystal structure of Cordyceps militaris IDCase in complex with 5-nitro-uracil

Summary for 4HK6

Entry DOI	10.2210/pdb4hk6/pdb
Related	4HJW 4HK5 4HK6
Descriptor	Uracil-5-carboxylate decarboxylase, ZINC ION, 5-nitrouracil, ... (4 entities in total)
Functional Keywords	pyrimidine metabolism, dna decarboxylation, idcase, decarboxylase, uracil, lyase
Biological source	Cordyceps militaris (Caterpillar fungus)
Total number of polymer chains	4
Total formula weight	169159.61
Authors	Xu, S.,Zhu, J.,Ding, J. (deposition date: 2012-10-15, release date: 2013-09-11, Last modification date: 2023-09-20)
Primary citation	Xu, S.,Li, W.,Zhu, J.,Wang, R.,Li, Z.,Xu, G.L.,Ding, J. Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase. Cell Res., 23:1296-1309, 2013 Cited by PubMed: 23917530 DOI: 10.1038/cr.2013.107 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation