4HI3
Crystal structure of dimeric R298A mutant of SARS coronavirus main protease
Summary for 4HI3
Entry DOI | 10.2210/pdb4hi3/pdb |
Descriptor | 3C-like proteinase (2 entities in total) |
Functional Keywords | chymotrypsin-like protein, protease, cytosol, hydrolase |
Biological source | SARS coronavirus |
Cellular location | Non-structural protein 3: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 4: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 6: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 7: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 8: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 9: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 10: Host cytoplasm, host perinuclear region (By similarity): P0C6U8 |
Total number of polymer chains | 2 |
Total formula weight | 69985.71 |
Authors | Wu, C.-G.,Chou, C.-Y. (deposition date: 2012-10-11, release date: 2013-05-01, Last modification date: 2023-09-20) |
Primary citation | Wu, C.G.,Cheng, S.C.,Chen, S.C.,Li, J.Y.,Fang, Y.H.,Chen, Y.H.,Chou, C.Y. Mechanism for controlling the monomer-dimer conversion of SARS coronavirus main protease. Acta Crystallogr.,Sect.D, 69:747-755, 2013 Cited by PubMed: 23633583DOI: 10.1107/S0907444913001315 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.09 Å) |
Structure validation
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