4HI3

Crystal structure of dimeric R298A mutant of SARS coronavirus main protease

4HI3 の概要

• エントリーDOI: 10.2210/pdb4hi3/pdb
• 分子名称: 3C-like proteinase (2 entities in total)
• 機能のキーワード: chymotrypsin-like protein, protease, cytosol, hydrolase
• 由来する生物種: SARS coronavirus
• 細胞内の位置: Non-structural protein 3: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 4: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 6: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 7: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 8: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 9: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 10: Host cytoplasm, host perinuclear region (By similarity): P0C6U8
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 69985.71

構造登録者

Wu, C.-G.,Chou, C.-Y. (登録日: 2012-10-11, 公開日: 2013-05-01, 最終更新日: 2023-09-20)

• 主引用文献: Wu, C.G.,Cheng, S.C.,Chen, S.C.,Li, J.Y.,Fang, Y.H.,Chen, Y.H.,Chou, C.Y.; Mechanism for controlling the monomer-dimer conversion of SARS coronavirus main protease.; Acta Crystallogr.,Sect.D, 69:747-755, 2013; PubMed: 23633583; DOI: 10.1107/S0907444913001315

実験手法

X-RAY DIFFRACTION (2.09 Å)