4HGM
Shark IgNAR Variable Domain
Summary for 4HGM
Entry DOI | 10.2210/pdb4hgm/pdb |
Related | 4HGK |
Descriptor | Shark V-NAR, Serum albumin, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | ig-fold, human albumin, v-nar, immune system |
Biological source | Squalus acanthias (Dogfish Shark) More |
Cellular location | Secreted: P02768 |
Total number of polymer chains | 2 |
Total formula weight | 79038.93 |
Authors | Olland, A.,Kovalenko, O.V.,King, D.,Svenson, K. (deposition date: 2012-10-08, release date: 2013-05-08, Last modification date: 2024-03-06) |
Primary citation | Kovalenko, O.V.,Olland, A.,Piche-Nicholas, N.,Godbole, A.,King, D.,Svenson, K.,Calabro, V.,Muller, M.R.,Barelle, C.J.,Somers, W.,Gill, D.S.,Mosyak, L.,Tchistiakova, L. Atypical Antigen Recognition Mode of a Shark Immunoglobulin New Antigen Receptor (IgNAR) Variable Domain Characterized by Humanization and Structural Analysis. J.Biol.Chem., 288:17408-17419, 2013 Cited by PubMed: 23632026DOI: 10.1074/jbc.M112.435289 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.34 Å) |
Structure validation
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